Several years work - finally we did it
- Alan Richardson
- Jan 3, 2023
- 1 min read
I started a project in 2004. The reviewers of the grant proposal said it was impossible (I hope so much that particular reviewer is reading this!!!) I've published several papers along the way proving the reviewers wrong. But this one is special.
We started work on this part of the project in around 2015. Its taken 3 PhD students (Mohamed Abed, Suad Ibrahim, Gehad Mohamed) to finally get the data togeter to get it published. This paper is important to me because the original idea was mine, and with this we've discovered something truly novel - a way to make chemotherapy more effective in cancer patients (although new drugs will have to be developed before it can finally used in the clinic; we are on it, we just need funding). We could have published it much sooner (I think we presented it a conference in around 2016) but I wanted to be sure we got it right. I probably drove my students mad asking them to repeat experiments, but I think it was worth it.
Of all the work I have published, I think I am most proud of this. The article is here https://rdcu.be/c1LjP
If you look in the supplementary data there are some cool videos showing cells reversing cell division just before completing it. https://www.nature.com/articles/s41416-022-02095-9#Sec14
I probably ought to write something about "following your dreams" or "believe in yourself". But I prefer a made-up fake Latin quote my Dad told me: Nihil illigitimi carbarundum.

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